Prof. Lixian Wu Wu | Pharmacology | Best Researcher Award
Vice Dean at Fujian Medical University, China.
Dr. Lixian Wu ๐ is an accomplished pharmacologist from Fujian, China, with over 20 years of experience in anticancer drug research ๐. Her groundbreaking work includes DNA repair mechanisms ๐งฌ, tumor microenvironment interactions ๐งซ, and PROTAC-based drug design ๐งช. A distinguished researcher and mentor, she has led multiple national projects ๐, secured five patents ๐, and published influential scientific papers ๐. As a doctoral advisor, she has guided numerous Ph.D. and masterโs students ๐. Dr. Wuโs dedication to innovation and excellence has earned her the title of Fujian Provincial High-Level Talent ๐.
Professional Profile:
Suitability for Best Researcher Award โ Dr. Lixian Wu
Dr. Lixian Wu is highly suitable for the Best Researcher Award due to her sustained excellence in anticancer pharmacology research, innovative drug discovery, and academic mentorship over the past two decades. Her ability to translate complex molecular mechanisms into potential therapeutic strategiesโsuch as PROTAC-based compounds and immune-targeted therapiesโdemonstrates a deep and ongoing commitment to impactful, high-quality science. She has also contributed significantly to Chinaโs biomedical innovation ecosystem through patents, national-level research leadership, and talent cultivation.
๐ Education & Experience
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๐ Bachelorโs Degree in Clinical Medicine โ Fujian Medical University, China
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๐งช Masterโs Degree (M.D.) in Pharmacology โ Fujian Medical University
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๐งฌ Ph.D. in Pharmacology โ Fujian Medical University
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๐ง 20+ years of research experience in anticancer pharmacology
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๐งโ๐ซ Doctoral Tutor mentoring 8 Ph.D. and 20 Masterโs students
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๐ Principal Investigator for 4 National Natural Science Foundation projects
๐ Professional Developmentย
Dr. Wu has continually advanced her professional journey through innovative research and academic leadership ๐. She has synthesized and screened high-efficacy anticancer compounds via PROTAC technology ๐งช, explored immune-based cancer therapy through NKT cell modulation ๐ฌ, and discovered novel feedback loops in DNA repair pathways ๐งฌ. She remains actively engaged in national-level scientific funding programs ๐ and contributes to the field through patents and impactful publications ๐. Her mentorship has nurtured the next generation of pharmacologists ๐ฉโ๐ฌ๐จโ๐ฌ, enhancing Chinaโs scientific landscape. Her evolving research and professional expertise position her as a thought leader in oncology drug discovery ๐.
๐งช Research Focus Category
Dr. Wuโs research primarily centers on anticancer pharmacology ๐, particularly the molecular mechanisms of cancer progression and therapy ๐งฌ. Her work targets DNA repair pathways, unveiling the regulatory roles of NF-kB and PARP1 in tumor survival ๐. She also explores the tumor microenvironment, focusing on the immune systemโs role in fighting cancer, especially through NKT cells ๐งซ. Leveraging PROTAC technology, she has developed degradation-based drug strategies with high therapeutic potential โ๏ธ. Her multi-dimensional approach places her research at the crossroads of immunopharmacology, molecular biology, and drug design, making a significant impact on cancer therapeutics ๐ฌ.
๐ Awards and Honors
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๐ Fujian Provincial High-Level Talent recognition
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๐ Principal Investigator of 4 National Natural Science Foundation of China (NSFC) grants
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๐งช Holder of 5 Chinese Invention Patents in anticancer drug development
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๐ Author of several influential SCI-indexed research papers
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๐ Mentor to 8 Ph.D. and 20 Masterโs students
Publication Top Notes
๐งฌ Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma โ iScience (2024) | Cited by: 1
๐ Ferroptosis boosted oral cancer photodynamic therapy by carrier-free Sorafenib-Ce6 self-assembly nanoparticles โ Journal of Controlled Release (2024) | Cited by: 22
๐ฌ Discovery of X10g as a selective PROTAC degrader of Hsp90ฮฑ protein for treating breast cancer โ European Journal of Medicinal Chemistry (2023) | Cited by: 5
๐งช Synthesis of Novel Dual Target Inhibitors of CDK12 and PARP1 and Their Antitumor Activities in HER2-Positive Breast Cancers โ ACS Omega (2023) | Cited by: 3